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It's been almost three decades since the rage virus escaped a biological weapons laboratory, and now, still in an enforced quarantine, people have found ways to exist amidst the infected. A group of survivors live on a small island connected to the mainland by a single, heavily defended causeway. When one of them leaves the island on a mission into the dark heart of the mainland, he discovers secrets, wonders, and horrors that have mutated not only the infected but other survivors as well.