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18 year-old Jay has had enough of life. 28 year-old Liz can't get enough of it. And as Jay stands on a cliff top contemplating putting an end to the meaningless miasma of his existence, Liz lands in town on the latest leg of her endless adventures backpacking the globe. After a sliding doors moment brings this unlikely pair together, they form a deep and immediate bond - much to the chagrin of Jay's privileged but jaded socialite parents. Unfortunately, Liz's laissez-faire lifestyle is brought to an abrupt halt by a rare and exotic illness known as coccidioidomycosis and, as Jay becomes more and more entwined in her plight, all four are forced to come to terms with their world views in this harrowing, provocative, yet ultimately uplifting saga.