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In a post-apocalyptic world plagued by a fungal disease turning humans into flesh-eating monsters, hope resides in a group of children who are hybrids, retaining intellect while craving flesh. Dr. Caldwell conducts experiments on them, while teacher Helen forms a bond with Melanie, an exceptional girl among them. When the base is overrun, they escape with soldiers, facing dangers and moral dilemmas on a journey to save humanity.