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Chandra Wisnu is thought to be one of the few people in the world with a rare skin disease which causes large, bubble like lumps to develop all over his body. His skin has been so badly ravaged by tumours he is known as The Bubble Man. His horrible condition has taken over his life; he rarely leaves his house and when he does he is forced to cover his face with a balaclava and wear sunglasses for fear of frightening or being ridiculed by others. And now, symptoms of this condition are appearing in his two adult children. This film follows world renowned dermatologist Dr. Anthony Gaspari as he travels to Indonesia to try to find a cure for Chandra and save his children from the affliction that he has endured since he was 19.