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An outbreak of rabies among persons who underwent an experimental gene therapy is sweeping the country. They have all been scarred, but unaware when to begin to have symptoms. To avoid infections, the government decided to confine the victims in detention centers, but a group manages to escape and hide in an abandoned shelter. Filmed between Madrid and Malaga, "Rage" tells the drama of people facing an extreme situation in which the coexistence of a group of fugitives became the cornerstone that articulates an entire plot.