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Jhuma e Niladri are a couple from Burdwan in the state of West Bengal. They have been married for 8 years and have no children. This is a major problem, especially in India where a childless married woman is considered impure. A few years ago, Niladri would probably have abandoned Jhuma, and her life would have become a misery, her presence taken to be an inauspicious sign at social events or religious ceremonies. Today, cutting-edge research and the boom in the assisted reproduction industry offer them new possibilities, new hopes, new dilemmas. The couple set off for Hyderabad, the heart of Indian medical and assisted reproduction research, on a journey of hope, a journey that will take them to Dr Rama's fertility clinic. Dr Rama is the owner of a number of clinics in southern India and is expanding her business into the Gulf States and the Caribbean. At the Hyderabad clinic, Jhuma comes into contact with doctors, embryologists, other infertile women and surrogate mothers.