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Brenna Caitlin Otts, who is of Irish and English descent, was born in Fairfax, Virginia but relocated to rural Colorado when her parents divorced at the age of 3. After graduating high school valedictorian, Otts attended Colorado State University where she majored in Theatre. While there, Otts began her professional acting career in nearby Denver, snagging her first lead role in a feature before graduating a year early and moving to Los Angeles. She booked her first network television speaking role on the HBO hit series "Westworld" and began working steadily in the industry from then on out, acquiring her first recurring role on the CBS All Access cult classic "Strange Angel" in 2019.