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While a teenager Barlow won a national talent search Festival4Stars. In 2008, Barlow took part 'The Stobart Factor' a talent competition, which was judged by The X Factor judge Louis Walsh. Walsh gave Barlow positive comments on her singing and told her she had 'style'. Alice went on to win the competition and won £10,000, in which she put towards an Invisalign to straighten her teeth. In October 2009, Alice made her television debut as Rae Wilson in Channel 4, Soap-opera, Hollyoaks. While at Hollyoaks, Barlow won an All About Soap award for "Best Love Triangle", along with Kieron Richardson and Emmett J. Scanlan. In early 2011, Alice decided to leave the serial and her character was killed off in the late night spin-off Hollyoaks Later, which aired in September 2011. Alices departure was kept a secret until her exit scenes were aired. While starring in the show she also presented linked project The Hollyoaks Music Show. In 2012 Alice secured the role of Bella in ITV drama series Crime Stories. On 15 February 2013, Digital Spy reported that Alice had auditioned on the second series of The Voice UK and has got through to the next round with Danny O'Donoghue as her coach. Alice was defeated in the battle rounds (unjustly) by Andrea Begley, the eventual winner of the show. Following her elimination from the talent contest Alice vowed to continue her ambition of a career in music. On 10 July, Alice's management announced that she had secured the role of Sara in a new E4's comedy titled Drifters. In 2014, Barlow filmed a guest appearance for the medical drama Casualty. For 2015, Alice secured a recurring role in ITV comedy Benidorm and a guest role in Russell T Davies' series Banana. As of 2018 Alice is venturing into the world of theatre making her debut in the new dusty Springfield musical son of a preacher man playing the role of Kat (which she does exceptionally well).